Immunoregulatory networks in human Chagas disease
نویسندگان
چکیده
منابع مشابه
Immunoregulatory networks in human Chagas disease.
Chagas disease, caused by the infection with Trypanosoma cruzi, is endemic in all Latin America. Due to the increase in population migration, Chagas disease has spread worldwide and is now considered a health issue not only in endemic countries. While most chronically infected individuals remain asymptomatic, approximately 30% of the patients develop a potentially deadly cardiomyopathy. The exa...
متن کاملImmunoregulatory mechanisms in Chagas disease: modulation of apoptosis in T-cell mediated immune responses.
BACKGROUND Chronic Chagas disease presents different clinical manifestations ranging from asymptomatic (namely indeterminate) to severe cardiac and/or digestive. Previous results have shown that the immune response plays an important role, although no all mechanisms are understood. Immunoregulatory mechanisms such as apoptosis are important for the control of Chagas disease, possibly affecting ...
متن کاملChagas disease and human migration.
Human Chagas disease is a purely accidental occurrence. As humans came into contact with the natural foci of infection might then have become infected as a single addition to the already extensive host range of Trypanosoma cruzi that includes other primates. Thus began a process of adaptation and domiciliation to human habitations through which the vectors had direct access to abundant food as ...
متن کاملCognitive impairment in human chronic Chagas' disease.
UNLABELLED We proposed to investigate subclinical cognitive impairment secondary to chronic Chagas' disease (CCD). No similar study was previously done. The neuropsychological performance of 45 chronic Chagasic patients and 26 matched controls (age, education place and years of residency in endemic area) was compared using the Mini Mental State Exam (MMSE), Weschler Memory Scale (WMS) and the W...
متن کاملTroponin in chagas disease.
Chagas disease is still a major tropical disease in Latin America, affecting 16 to 18 million people. About 6 million people are infected with the causative organism, Trypanosoma cruzi, in Brazil [1]. However, it often remains for decades in its indeterminate form, symptomless, with tissue injury in about 30% of the cases, which eventually will evolve to serious arrhythmia and sudden death [1]....
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ژورنال
عنوان ژورنال: Parasite Immunology
سال: 2014
ISSN: 0141-9838
DOI: 10.1111/pim.12107